Dubai's measure drops from Wednesday's 20-week high as investors take weak global cues to book profits ahead of the weekend, while most other markets end near-flat.
The emirate's index falls 0.7 percent to 1,605 points, trimming year-to-date gains to 18.6 percent.
Emaar Properties was the main drag, falling 1.4 percent. Emirates NBD shed 0.7 percent and Dubai Financial Market lost 1.9 percent.
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